Beyond comparisons of means: understanding changes in gene expression at the single-cell level
Traditional differential expression tools are limited to detecting changes in overall expression, and fail to uncover the rich information provided by single-cell level data sets. We present a Bayesian hierarchical model that builds upon BASiCS to study changes that lie beyond comparisons of means,...
Main Authors: | Vallejos, Catalina A., Richardson, Sylvia, Marioni, John C. |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832562/ |
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