RNA-Seq Gene Profiling - A Systematic Empirical Comparison

Accurately quantifying gene expression levels is a key goal of experiments using RNA-sequencing to assay the transcriptome. This typically requires aligning the short reads generated to the genome or transcriptome before quantifying expression of pre-defined sets of genes. Differences in the alignme...

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Bibliographic Details
Main Authors: Fonseca, Nuno A., Marioni, John, Brazma, Alvis
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182317/