A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor

Single-cell RNA sequencing (scRNA-seq) is widely used to profile the transcriptome of individual cells. This provides biological resolution that cannot be matched by bulk RNA sequencing, at the cost of increased technical noise and data complexity. The differences between scRNA-seq and bulk RNA-seq...

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Bibliographic Details
Main Authors: Lun, Aaron T.L., McCarthy, Davis J., Marioni, John C.
Format: Online
Language:English
Published: F1000Research 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112579/