Forced Ambiguity of the Leucine Codons for Multiple-Site-Specific Incorporation of a Noncanonical Amino Acid
Multiple-site-specific incorporation of a noncanonical amino acid into a recombinant protein would be a very useful technique to generate multiple chemical handles for bioconjugation and multivalent binding sites for the enhanced interaction. Previously combination of a mutant yeast phenylalanyl-tRN...
Main Authors: | Kwon, Inchan, Choi, Eun Sil |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814082/ |
Similar Items
-
Sense codon emancipation for proteome-wide incorporation of noncanonical amino acids: rare isoleucine codon AUA as a target for genetic code expansion
by: Bohlke, Nina, et al.
Published: (2014) -
Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acids
by: Fan, Chenguang, et al.
Published: (2015) -
The Fungus Candida albicans Tolerates Ambiguity at Multiple Codons
by: Simões, João, et al.
Published: (2016) -
Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design
by: Renfrew, P. Douglas, et al.
Published: (2012) -
Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
by: Worst, Emanuel G., et al.
Published: (2016)