Sense codon emancipation for proteome-wide incorporation of noncanonical amino acids: rare isoleucine codon AUA as a target for genetic code expansion
One of the major challenges in contemporary synthetic biology is to find a route to engineer synthetic organisms with altered chemical constitution. In terms of core reaction types, nature uses an astonishingly limited repertoire of chemistries when compared with the exceptionally rich and diverse m...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
BlackWell Publishing Ltd
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237120/ |