High fat diet impairs the function of glucagon-like peptide-1 producing L-cells

High fat diet impairs the function of glucagon-like peptide-1 producing L-cells

•Long term dietary changes impair function of the gut endocrine system.•High fat diet impairs nutrient-triggered GLP-1 release from murine small intestine.•L-cells from HFD-fed mice have reduced expression of many L-cell-specific genes.

Bibliographic Details
Main Authors: Richards, Paul, Pais, Ramona, Habib, Abdella M., Brighton, Cheryl A., Yeo, Giles S.H., Reimann, Frank, Gribble, Fiona M.
Format: Online
Language:English
Published: Elsevier Science Inc 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788507/

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