Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
Comparison of autophagy inhibition by deletion of Atg5, Atg16L1, Atg7, or Fip200 reveals a critical role for increased p62 in determining the fate of autophagy-deficient neural stem cells by controlling intracellular superoxide.
Main Authors: | Wang, Chenran, Chen, Song, Yeo, Syn, Karsli-Uzunbas, Gizem, White, Eileen, Mizushima, Noboru, Virgin, Herbert W., Guan, Jun-Lin |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772497/ |
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