Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

Comparison of autophagy inhibition by deletion of Atg5, Atg16L1, Atg7, or Fip200 reveals a critical role for increased p62 in determining the fate of autophagy-deficient neural stem cells by controlling intracellular superoxide.

Bibliographic Details
Main Authors: Wang, Chenran, Chen, Song, Yeo, Syn, Karsli-Uzunbas, Gizem, White, Eileen, Mizushima, Noboru, Virgin, Herbert W., Guan, Jun-Lin
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772497/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772497/

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