Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
Comparison of autophagy inhibition by deletion of Atg5, Atg16L1, Atg7, or Fip200 reveals a critical role for increased p62 in determining the fate of autophagy-deficient neural stem cells by controlling intracellular superoxide.
Bibliographic Details
Main Authors: |
Wang, Chenran,
Chen, Song,
Yeo, Syn,
Karsli-Uzunbas, Gizem,
White, Eileen,
Mizushima, Noboru,
Virgin, Herbert W.,
Guan, Jun-Lin |
Format: | Online
|
Language: | English |
Published: |
The Rockefeller University Press
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772497/
|