Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway

Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway

Angiosarcomas are rare malignant mesenchymal tumors of endothelial differentiation. The clinical behavior is usually aggressive and the prognosis for patients with advanced disease is poor with no effective therapies. The genetic bases of these tumors have been partially revealed in recent studies r...

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Bibliographic Details
Main Authors: Murali, Rajmohan, Chandramohan, Raghu, Möller, Inga, Scholz, Simone L., Berger, Michael, Huberman, Kety, Viale, Agnes, Pirun, Mono, Socci, Nicholas D., Bouvier, Nancy, Bauer, Sebastian, Artl, Monika, Schilling, Bastian, Schimming, Tobias, Sucker, Antje, Schwindenhammer, Benjamin, Grabellus, Florian, Speicher, Michael R., Schaller, Jörg, Hillen, Uwe, Schadendorf, Dirk, Mentzel, Thomas, Cheng, Donavan T., Wiesner, Thomas, Griewank, Klaus G.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742160/

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