TERT Promoter Mutations Are Frequent in Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma

TERT Promoter Mutations Are Frequent in Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma

Activating mutations in the TERT promoter were recently identified in up to 71% of cutaneous melanoma. Subsequent studies found TERT promoter mutations in a wide array of other major human cancers. TERT promoter mutations lead to increased expression of telomerase, which maintains telomere length an...

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Bibliographic Details
Main Authors: Griewank, Klaus G., Murali, Rajmohan, Schilling, Bastian, Schimming, Tobias, Möller, Inga, Moll, Iris, Schwamborn, Marion, Sucker, Antje, Zimmer, Lisa, Schadendorf, Dirk, Hillen, Uwe
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832433/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832433/

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