Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data
A large number of computational methods have been developed for analyzing differential gene expression in RNA-seq data. We describe a comprehensive evaluation of common methods using the SEQC benchmark dataset and ENCODE data. We consider a number of key features, including normalization, accuracy o...
Main Authors: | , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
BioMed Central
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054597/ |