Designing malaria vaccines to circumvent antigen variability✩
Prospects for malaria eradication will be greatly enhanced by an effective vaccine, but parasite genetic diversity poses a major impediment to malaria vaccine efficacy. In recent pre-clinical and field trials, vaccines based on polymorphic Plasmodium falciparum antigens have shown efficacy only agai...
Main Authors: | Ouattara, Amed, Barry, Alyssa E., Dutta, Sheetij, Remarque, Edmond J., Beeson, James G., Plowe, Christopher V. |
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Format: | Online |
Language: | English |
Published: |
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731100/ |
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