Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response

Antigen receptor diversity underpins adaptive immunity by providing the ground for clonal selection of lymphocytes with the appropriate antigen reactivity. Current models attribute T cell clonal selection during the immune response to T-cell receptor (TCR) affinity for either foreign or self peptide...

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Bibliographic Details
Main Authors: Merkenschlager, Julia, Ploquin, Mickaël J., Eksmond, Urszula, Andargachew, Rakieb, Thorborn, Georgina, Filby, Andrew, Pepper, Marion, Evavold, Brian, Kassiotis, George
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728444/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728444/

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