Negative Selection by an Endogenous Retrovirus Promotes a Higher-Avidity CD4+ T Cell Response to Retroviral Infection

Effective T cell responses can decisively influence the outcome of retroviral infection. However, what constitutes protective T cell responses or determines the ability of the host to mount such responses is incompletely understood. Here we studied the requirements for development and induction of C...

Full description

Bibliographic Details
Main Authors: Young, George R., Ploquin, Mickaƫl J.-Y., Eksmond, Urszula, Wadwa, Munisch, Stoye, Jonathan P., Kassiotis, George
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349761/