Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus

CD4+ T cells develop distinct and often contrasting helper, regulatory, or cytotoxic activities. Typically a property of CD8+ T cells, granzyme-mediated cytotoxic T cell (CTL) potential is also exerted by CD4+ T cells. However, the conditions that induce CD4+ CTLs are not entirely understood. Using...

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Bibliographic Details
Main Authors: Donnarumma, Tiziano, Young, George R., Merkenschlager, Julia, Eksmond, Urszula, Bongard, Nadine, Nutt, Stephen L., Boyer, Claude, Dittmer, Ulf, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko, Bayer, Wibke, Kassiotis, George
Format: Online
Language:English
Published: Cell Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149578/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149578/

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