A Simple and Rapid LC-MS/MS Method for the Determination of BMCL26 a Novel Anti-Parasitic Agent in Rat Plasma

A Simple and Rapid LC-MS/MS Method for the Determination of BMCL26 a Novel Anti-Parasitic Agent in Rat Plasma

BMCL26 is a potential drug derived from nimesulide, which has exhibited the substantial anti-parasitic activity in various cell lines. To conduct various pharmacological and toxicological properties of this drug, we developed and validated a rapid LC-MS/MS method for its quantification in accordance...

Full description

Bibliographic Details
Main Authors:	Voggu, Ramakrishna R, Zhou, Xiang, Su, Bin, Guo, Baochuan
Format:	Online
Language:	English
Published:	2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727756/

Similar Items

GOAT – A simple LC-MS/MS gradient optimization tool
by: Trudgian, David C, et al.
Published: (2014)

LC-MS/MS simulatneous determination of itopride hydrochloride and domperidone in human plasma
by: Bose, Anirbandeep, et al.
Published: (2009)

Analytical Challenges: Determination of Tetrodotoxin in Human Urine and Plasma by LC-MS/MS
by: Leung, Kelvin Sze-Yin, et al.
Published: (2011)

Quantification of cGMP in human plasma by isotope dilution LC-MS/MS
by: Martens-Lobenhoffer, Jens, et al.
Published: (2009)

Simple and Robust Analysis of Cefuroxime in Human Plasma by LC-MS/MS: Application to a Bioequivalence Study
by: Hu, Xingjiang, et al.
Published: (2014)

Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application
by: Liu, Yanping, et al.
Published: (2013)

Quantitation of tadalafil in human plasma using a sensitive and rapid LC-MS/MS method for a bioequivalence study
by: Abhaysingh Bhadoriya, et al.
Published: (2018-08-01)

Rapid evaluation of 25 key sphingolipids and phosphosphingolipids in human plasma by LC-MS/MS
by: Basit, Abdul, et al.
Published: (2015)

Integrated LC-MS/MS system for plant metabolomics
by: Sawada, Yuji, et al.
Published: (2013)

Largazole Pharmacokinetics in Rats by LC-MS/MS
by: Yu, Mingming, et al.
Published: (2014)

Simultaneous Determination of Atorvastatin and Aspirin in Human Plasma by LC–MS/MS: Its Pharmacokinetic Application
by: Gajula, Ramakrishna, et al.
Published: (2012)

In Vivo Metabolism Study of Xiamenmycin A in Mouse Plasma by UPLC-QTOF-MS and LC-MS/MS
by: Lei, Feng, et al.
Published: (2015)

Evaluation of Acrylamide in Food from China by a LC/MS/MS Method
by: Chen, Yong-Hong, et al.
Published: (2012)

Rapid, Validated UPLC-MS/MS Method for Determination of Glibenclamide in Rat Plasma
by: Mohd Aftab Alam, et al.
Published: (2018-01-01)

Development of LC/MS-MS method for analysis of polyphenols in Malaysian traditional vegetables
by: Haron, Normah, et al.
Published: (2015)

Ion pairing LC-MS/MS method for analysis of intracellular phosphorylated metabolites
by: Utami, Wahyu
Published: (2015)

Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC–MS/MS and evaluation of their stability in mice tissues
by: Krijt, Jakub, et al.
Published: (2009)

Deep and Highly Sensitive Proteome Coverage by LC-MS/MS Without Prefractionation*
by: Thakur, Suman S., et al.
Published: (2011)

Analysis and Exposure Assessment of Perchlorate in Korean Dairy Products with LC-MS/MS
by: Oh, Sung-Hee, et al.
Published: (2011)

MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data
by: Hartler, Jürgen, et al.
Published: (2007)

Inferring serum proteolytic activity from LC-MS/MS data
by: Dittwald, Piotr, et al.
Published: (2012)

Quantitation of cyclic dinucleotides by reversed-phase LC-MS/MS
by: Spangler, Christian, et al.
Published: (2009)

Whole gel processing procedure for GeLC-MS/MS based proteomics
by: Piersma, Sander R, et al.
Published: (2013)

Optimal precursor ion selection for LC-MALDI MS/MS
by: Zerck, Alexandra, et al.
Published: (2013)

Comparative Analysis of Biological Sphingolipids with Glycerophospholipids and Diacylglycerol by LC-MS/MS
by: Ogiso, Hideo, et al.
Published: (2014)

LC-MS and GC-MS based metabolomics platform for cancer research
by: Lu, Wenyun, et al.
Published: (2014)

LC–MS/MS Method for the Simultaneous Determination of Free Urinary Steroids
by: Allende, Fidel, et al.
Published: (2014)

LC-MS/MS-based multibiomarker approaches for the assessment of human exposure to mycotoxins
by: Warth, Benedikt, et al.
Published: (2013)

Development of LC-MS/MS confirmatory method for the determination of testosterone in bovine serum
by: Woźniak Barbara, et al.
Published: (2017-03-01)

Investigations of the Copper Peptide Hepcidin-25 by LC-MS/MS and NMR
by: Ioana M. Abbas, et al.
Published: (2018-08-01)

Identification and Assessment of Octreotide Acylation in Polyester Microspheres by LC–MS/MS
by: Shirangi, Mehrnoosh, et al.
Published: (2015)

Visualization of LC‐MS/MS proteomics data in MaxQuant
by: Tyanova, Stefka, et al.
Published: (2015)

Dataset of mouse hippocampus profiled by LC–MS/MS for label-free quantitation
by: English, Jane A., et al.
Published: (2016)

Quantitative LC-MS/MS Analysis of Proteins Involved in Metastasis of Breast Cancer
by: Goto, Rieko, et al.
Published: (2015)

LC–MS-MS Analysis of Urinary Biomarkers of Imazalil Following Experimental Exposures
by: Faniband, Moosa H., et al.
Published: (2015)

Characterization of the Oxidative Degradation Product of Darunavir by LC-MS/MS
by: Yamjala, Karthik, et al.
Published: (2015)

Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS
by: Bilgin, Mesut, et al.
Published: (2016)

Development Rapid Analytical Methods for Inositol as a Trace Component by HPLC and LC-MS/MS in Infant Formula
by: Shin, Jin-Ho, et al.
Published: (2015)

Development of a Rapid LC-MS/MS Method for the Determination of Emerging Fusarium mycotoxins Enniatins and Beauvericin in Human Biological Fluids
by: Serrano, Ana Belén, et al.
Published: (2015)

Hair-based rapid analyses for multiple drugs in forensics and doping: application of dynamic multiple reaction monitoring with LC-MS/MS
by: Shah, Iltaf, et al.
Published: (2014)