LC–MS/MS Method for the Simultaneous Determination of Free Urinary Steroids

Cortisol homeostasis is implicated in hypertension and metabolic syndrome. Two enzymes modulate cortisol availability; 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) preferentially converts inactive cortisone to cortisol, whereas 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) converts cortis...

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Bibliographic Details
Main Authors: Allende, Fidel, Solari, Sandra, Campino, Carmen, Carvajal, Cristian A., Lagos, Carlos F., Vecchiola, Andrea, Valdivia, Carolina, Baudrand, René, Owen, Gareth I., Fardella, Carlos E.
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967076/