GADD45a physically and functionally interacts with TET1

DNA demethylation plays a central role during development and in adult physiology. Different mechanisms of active DNA demethylation have been established. For example, Growth Arrest and DNA Damage 45-(GADD45) and Ten-Eleven-Translocation (TET) proteins act in active DNA demethylation but their funct...

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Bibliographic Details
Main Authors: Kienhöfer, Sabine, Musheev, Michael U., Stapf, Ulrike, Helm, Mark, Schomacher, Lars, Niehrs, Christof, Schäfer, Andrea
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673086/