Gadd45β and Gadd45γ are critical for regulating autoimmunity

The number of effector T cells is controlled by proliferation and programmed cell death. Loss of these controls on self-destructive effector T cells may precipitate autoimmunity. Here, we show that two members of the growth arrest and DNA damage-inducible (Gadd45) family, β and γ, are critical in th...

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Bibliographic Details
Main Authors: Liu, Lin, Tran, Elise, Zhao, Yani, Huang, Yuchen, Flavell, Richard, Lu, Binfeng
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212988/