The second virial coefficient as a predictor of protein aggregation propensity: A self-interaction chromatography study
The second osmotic virial coefficients (b2) of four proteins – lysozyme, recombinant human lactoferrin, concanavalin A and catalase were measured by self-interaction chromatography (SIC) in solutions of varying salt type, concentration and pH. Protein aggregate sizes based on the initial hydrodynami...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Science
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644993/ |