Size-Exclusion Chromatography for the Analysis of Protein Biotherapeutics and their Aggregates
In recent years, the use and number of biotherapeutics has increased significantly. For these largely protein-based therapies, the quantitation of aggregates is of particular concern given their potential effect on efficacy and immunogenicity. This need has renewed interest in size-exclusion chromat...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Taylor & Francis
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556795/ |