K-ras2 Activation and Genome Instability Increase Proliferation and Size of FAP Adenomas

The possible role of K‐ras2 mutations and aneuploidy toward increase of proliferation and adenoma size in Familial Adenomatous Polyposis (FAP) adenomas is not known. The present study addresses these issues by investigating 147 colorectal adenomas obtained from four FAP patients. The majority of ade...

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Bibliographic Details
Main Authors: Rapallo, Anna, Sciutto, Andrea, Geido, Elio, Orecchia, Roberto, Infusini, Edmondo, Pujic, Natalija, d’Amore, Emanuele S.G., Monaco, Roberto, Risio, Mauro, Rossini, Francesco P., Giaretti, Walter
Format: Online
Language:English
Published: IOS Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615181/