p53 Mutations and DNA Ploidy in Colorectal Adenocarcinomas

The p53 tumour suppressor gene has an important role in the the maintenance of genome stability and its mutational inactivation may be at the origin of aneuploidy in cancer cells. The aim of this study was to determine whether p53 mutations were associated to DNA aneuploidy, as assessed by flow cyto...

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Bibliographic Details
Main Authors: Campomenosi, Paola, Assereto, Paola, Bogliolo, Massimo, Fronza, Gilberto, Abbondandolo, Angelo, Capasso, Antonella, Bellomo, Patrizia F., Monaco, Roberto, Rapallo, Anna, Sciutto, Andrea, Orecchia, Roberto, Geido, Elio, Giaretti, Walter
Format: Online
Language:English
Published: IOS Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615187/