Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling

The receptor-interacting protein kinase 3 (RIPK3) plays crucial roles in programmed necrosis and innate inflammatory responses. However, a little is known about the involvement of RIPK3 in NKT cell-mediated immune responses. Here, we demonstrate that RIPK3 plays an essential role in NKT cell functio...

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Bibliographic Details
Main Authors: Kang, Young Jun, Bang, Bo-Ram, Han, Kyung Ho, Hong, Lixin, Shim, Eun-Jin, Ma, Jianhui, Lerner, Richard A., Otsuka, Motoyuki
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576739/