Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis

Necroptosis as a molecular program, rather than simply incidental cell death, was established by elucidating the roles of receptor interacting protein (RIP) kinases 1 and 3, along with their downstream partner, mixed lineage kinase-like domain protein (MLKL). Previous studies suggested that phosphog...

Full description

Bibliographic Details
Main Authors: Lu, Wei, Sun, Junhui, Yoon, Jeong Seon, Zhang, Yan, Zheng, Lixin, Murphy, Elizabeth, Mattson, Mark P., Lenardo, Michael J.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725845/