Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer

Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer

Glucocorticoids (GCs) have been widely used as coadjuvants in the treatment of solid tumours, but GC treatment may be associated with poor pharmacotherapeutic response or prognosis. The genomic action of GC in these tumours is largely unknown. Here we find that dexamethasone (Dex, a synthetic GC)-re...

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Bibliographic Details
Main Authors: Chen, Zhong, Lan, Xun, Wu, Dayong, Sunkel, Benjamin, Ye, Zhenqing, Huang, Jiaoti, Liu, Zhihua, Clinton, Steven K., Jin, Victor X., Wang, Qianben
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573460/

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