Androgen receptor modulates Foxp3 expression in CD4+CD25+Foxp3+ regulatory T-cells

Androgen receptor modulates Foxp3 expression in CD4+CD25+Foxp3+ regulatory T-cells

CD4+CD25+Foxp3+ Treg cells are crucial for the maintenance of immunological homeostasis. Androgens significantly induce Foxp3 expression in humans and regulate the differentiation of Treg cells. A functional androgen receptor–binding site is identified within the Foxp3 locus leading to epigenetic ch...

Full description

Bibliographic Details
Main Authors:	Walecki, Magdalena, Eisel, Florian, Klug, Jörg, Baal, Nelli, Paradowska-Dogan, Agnieszka, Wahle, Eva, Hackstein, Holger, Meinhardt, Andreas, Fijak, Monika
Format:	Online
Language:	English
Published:	The American Society for Cell Biology 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571343/

Similar Items

Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3+ and Foxp3− T cells
by: Franckaert, Dean, et al.
Published: (2015)

Higher Sensitivity of Foxp3+ Treg Compared to Foxp3- Conventional T Cells to TCR-Independent Signals for CD69 Induction
by: Bremser, Anna, et al.
Published: (2015)

Changes in Natural Foxp3+Treg but Not Mucosally-Imprinted CD62LnegCD38+Foxp3+Treg in the Circulation of Celiac Disease Patients
by: van Leeuwen, Marieke A., et al.
Published: (2013)

Regulatory CD4+Foxp3+ T Cells Control the Severity of Anaphylaxis
by: Kanjarawi, Reem, et al.
Published: (2013)

CD200R/Foxp3-mediated signalling regulates microglial activation
by: Yi, Min-Hee, et al.
Published: (2016)

The Ratios of CD8+ T Cells to CD4+CD25+ FOXP3+ and FOXP3- T Cells Correlate with Poor Clinical Outcome in Human Serous Ovarian Cancer
by: Preston, Claudia C., et al.
Published: (2013)

Human Umbilical Vein Endothelial Cells foster conversion of CD4+CD25−Foxp3− T cells into CD4+Foxp3+ Regulatory T Cells via Transforming Growth Factor-β
by: Oettel, Anika, et al.
Published: (2016)

FOXP3-specific immunity
by: Andersen, Mads Hald
Published: (2013)

Protective Effect of CXCR3+CD4+CD25+Foxp3+ Regulatory T Cells in Renal Ischemia-Reperfusion Injury
by: Jun, Cao, et al.
Published: (2015)

Identification of a FOXP3+CD3+CD56+ population with immunosuppressive function in cancer tissues of human hepatocellular carcinoma
by: Li, Xiaofeng, et al.
Published: (2015)

Validation and clinical correlation of triplex CD3, CD8 and FOXP3 IHC of tumor-infiltrating lymphocytes in follicular lymphoma
by: Mansfield, James, et al.
Published: (2014)

IL-33 Effect on Quantitative Changes of CD4+CD25highFOXP3+ Regulatory T Cells in Children with Type 1 Diabetes
by: Ryba-Stanisławowska, Monika, et al.
Published: (2016)

CD45RA-Foxp3high but not CD45RA+Foxp3low suppressive T regulatory cells increased in the peripheral circulation of patients with head and neck squamous cell carcinoma and correlated with tumor progression
by: Sun, Wei, et al.
Published: (2014)

Evaluation of CD4+ CD25+ FoxP3+ Regulatory T cells and FoxP3 and CTLA-4 gene Expression in Patients wwith Newly Diagnosed Tuberculosis in Northeast of Iran
by: Ghazalsofala, Roghayeh, et al.
Published: (2015)

Re-redefining Foxp3 function
by: Bashyam, Hema
Published: (2007)

Searching for the Achilles Heel of FOXP3
by: Lozano, Teresa, et al.
Published: (2013)

TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
by: Marie, Julien C., et al.
Published: (2005)

Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia
by: Ruprecht, Claudia R., et al.
Published: (2005)

Alteration of CD4+CD25+Foxp3+ T cell level in Kawasaki disease
by: Sohn, Su Ye, et al.
Published: (2011)

CD4+CD25+FOXP3+ Regulatory T Cells Suppress Anti-Tumor Immune Responses in Patients with Colorectal Cancer
by: Clarke, Sarah L., et al.
Published: (2006)

WASP regulates suppressor activity of human and murine CD4+CD25+FOXP3+ natural regulatory T cells
by: Marangoni, Francesco, et al.
Published: (2007)

The Wiskott-Aldrich syndrome protein is required for the function of CD4+CD25+Foxp3+ regulatory T cells
by: Maillard, Michel H., et al.
Published: (2007)

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
by: Liu, Weihong, et al.
Published: (2006)

Asthma Prevention by Lactobacillus Rhamnosus in a Mouse Model is Associated With CD4+CD25+Foxp3+ T Cells
by: Jang, Seong-Ok, et al.
Published: (2012)

Apoptosis Signaling Is Altered in CD4+CD25+FoxP3+ T Regulatory Lymphocytes in Pre-Eclampsia
by: Darmochwal-Kolarz, Dorota, et al.
Published: (2012)

FoxP3+ regulatory CD4 T cells control the generation of functional CD8 memory
by: de Goër de Herve, M.G., et al.
Published: (2012)

56 Increased Frequency of CD4+ CD25+ FOXP3- in Allergic Conjunctivitis Patients
by: Galicia-Carreón, Jorge, et al.
Published: (2012)

CD4+CD62L+ Central Memory T Cells Can Be Converted to Foxp3+ T Cells
by: Zhang, Xiaolong, et al.
Published: (2013)

Trichinella spiralis Infection Suppressed Gut Inflammation with CD4+CD25+Foxp3+ T Cell Recruitment
by: Cho, Min Kyoung, et al.
Published: (2012)

Ribavirin Does Not Impair the Suppressive Activity of Foxp3+CD4+CD25+ Regulatory T Cells
by: Lee, Jeewon, et al.
Published: (2013)

Increase in TGF-β Secreting CD4+CD25+ FOXP3+ T Regulatory Cells in Anergic Lepromatous Leprosy Patients
by: Saini, Chaman, et al.
Published: (2014)

CD4+CD25-Foxp3+ T cells: a marker for lupus nephritis?
by: Bonelli, Michael, et al.
Published: (2014)

Serial Changes of CD4+CD25+FoxP3+ Regulatory T Cell in Canine Model of Sepsis Induced by Endotoxin
by: YU, Dohyeon, et al.
Published: (2014)

CD4+CD25+FoxP3+ regulatory T cells and cytokines interact with estradiol in cases of missed abortion
by: CAO, WEIPING, et al.
Published: (2014)

Bee Venom Mitigates Cisplatin-Induced Nephrotoxicity by Regulating CD4+CD25+Foxp3+ Regulatory T Cells in Mice
by: Kim, Hyunseong, et al.
Published: (2013)

CD4+CD25−Foxp3+ T cells play a role in tuberculous hydrothorax rather than malignant hydrothorax
by: Tang, Ying, et al.
Published: (2015)

Functional defects in CD4+ CD25high FoxP3+ regulatory cells in ankylosing spondylitis
by: Guo, Huifang, et al.
Published: (2016)

Accumulation Mechanisms of CD4+CD25+FOXP3+ Regulatory T Cells in EBV-associated Gastric Carcinoma
by: Zhang, Na-na, et al.
Published: (2015)

Indirubin Increases CD4+CD25+Foxp3+ Regulatory T Cells to Prevent Immune Thrombocytopenia in Mice
by: Zhang, Aijun, et al.
Published: (2015)

Human and Mouse CD8+CD25+FOXP3+ Regulatory T Cells at Steady State and during Interleukin-2 Therapy
by: Churlaud, Guillaume, et al.
Published: (2015)