The Ratios of CD8+ T Cells to CD4+CD25+ FOXP3+ and FOXP3- T Cells Correlate with Poor Clinical Outcome in Human Serous Ovarian Cancer

The Ratios of CD8+ T Cells to CD4+CD25+ FOXP3+ and FOXP3- T Cells Correlate with Poor Clinical Outcome in Human Serous Ovarian Cancer

Ovarian cancer is an immune reactive malignancy with a complex immune suppressive network that blunts successful immune eradication. This suppressive microenvironment may be mediated by recruitment or induction of CD4+ regulatory T cells (Tregs). Our study sought to investigate the association of tu...

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Bibliographic Details
Main Authors: Preston, Claudia C., Maurer, Matthew J., Oberg, Ann L., Visscher, Daniel W., Kalli, Kimberly R., Hartmann, Lynn C., Goode, Ellen L., Knutson, Keith L.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828213/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828213/

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