A complex of ZO-1 and the BAR-domain protein TOCA-1 regulates actin assembly at the tight junction

A complex of ZO-1 and the BAR-domain protein TOCA-1 regulates actin assembly at the tight junction

An alternative splice in TOCA-1 targets it to tight junctions. KO of TOCA-1 results in increased flux and decreased tight junction membrane dynamics. Ultrastructural analysis shows actin accumulation at the adherens junction. Identification of the ZO-1/TOCA-1 complex provides insights into tight jun...

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Bibliographic Details
Main Authors:	Van Itallie, Christina M., Tietgens, Amber Jean, Krystofiak, Evan, Kachar, Bechara, Anderson, James M.
Format:	Online
Language:	English
Published:	The American Society for Cell Biology 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571337/

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