Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid

Stereocilia of the inner ear’s sensory hair cells are filled with a paracrystalline array of parallel actin filaments. Krey et al. show that the actin cross-linker plastin-1 is needed for random liquid packing of actin filaments and final stereocilia diameter.

Bibliographic Details
Main Authors: Krey, Jocelyn F., Krystofiak, Evan S., Dumont, Rachel A., Vijayakumar, Sarath, Choi, Dongseok, Rivero, Francisco, Kachar, Bechara, Jones, Sherri M., Barr-Gillespie, Peter G.
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119939/