Backbone 1H, 13C, and 15N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein
The Fc portion of immunoglobulin G (IgG) recruits complements and its cognate receptors, thereby promoting defensive mechanisms in the humoral immune system. These effector functions critically depend on N-glycosylation at the Fc region, which is therefore regarded as a crucial factor in the design...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer Netherlands
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568019/ |