NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities

NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities

Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) is an important target for antiviral therapy against acquired immunodeficiency syndrome. However, the efficiency of available drugs is impaired most typically by drug-resistance mutations in this enzyme. In this study, we applied a...

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Bibliographic Details
Main Authors: Thammaporn, Ratsupa, Yagi-Utsumi, Maho, Yamaguchi, Takumi, Boonsri, Pornthip, Saparpakorn, Patchreenart, Choowongkomon, Kiattawee, Techasakul, Supanna, Kato, Koichi, Hannongbua, Supa
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625163/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625163/

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