Positive Selection on Loci Associated with Drug and Alcohol Dependence

Much of the evolution of human behavior remains a mystery, including how certain disadvantageous behaviors are so prevalent. Nicotine addiction is one such phenotype. Several loci have been implicated in nicotine related phenotypes including the nicotinic receptor gene clusters (CHRNs) on chromosome...

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Bibliographic Details
Main Authors: Sadler, Brooke, Haller, Gabe, Edenberg, Howard, Tischfield, Jay, Brooks, Andy, Kramer, John, Schuckit, Marc, Nurnberger, John, Goate, Alison
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536217/