Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy

In the U.S.A., cocaine is the second most abused illicit drug. Variants within the CHRNB3-A6 gene cluster have been associated with cigarette consumption in several GWAS. These receptors represent intriguing candidates for the study of cocaine dependence because nicotinic receptors are thought to be...

Full description

Bibliographic Details
Main Authors: Sadler, Brooke, Haller, Gabe, Agrawal, Arpana, Culverhouse, Rob, Bucholz, Kathleen, Brooks, Andy, Tischfield, Jay, Johnson, Eric O., Edenberg, Howard, Schuckit, Marc, Saccone, Nancy, Bierut, Laura, Goate, Alison
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894386/