Dosage Transmission Disequilibrium Test (dTDT) for Linkage and Association Detection

Both linkage and association studies have been successfully applied to identify disease susceptibility genes with genetic markers such as microsatellites and Single Nucleotide Polymorphisms (SNPs). As one of the traditional family-based studies, the Transmission/Disequilibrium Test (TDT) measures th...

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Bibliographic Details
Main Authors: Zhang, Zhehao, Wang, Jen-Chyong, Howells, William, Lin, Peng, Agrawal, Arpana, Edenberg, Howard J., Tischfield, Jay A., Schuckit, Marc A., Bierut, Laura J., Goate, Alison, Rice, John P.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653954/