Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway

Fibronectin adhesion stimulation of focal adhesion kinase (FAK)–Src–PI3K is an upstream regulatory branch of the Hippo pathway and stimulates the activity and nuclear localization of YAP in a Lats-dependent manner.

Bibliographic Details
Main Authors: Kim, Nam-Gyun, Gumbiner, Barry M.
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523609/