Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition

Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition

Epithelial to mesenchymal transition (EMT) is a key process in embryonic development and has been associated with cancer metastasis and drug resistance. For example, in EGFR mutated non-small cell lung cancers (NSCLC), EMT has been associated with acquired resistance to the EGFR inhibitor erlotinib....

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Bibliographic Details
Main Authors: Wilson, Catherine, Nicholes, Katrina, Bustos, Daisy, Lin, Eva, Song, Qinghua, Stephan, Jean-Philippe, Kirkpatrick, Donald S., Settleman, Jeff
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202126/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202126/

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