Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition

Adhesion signaling of integrin adhesion complexes (IACs) is sensitive to inhibition of key IAC kinases (FAK and/or Src), but IAC composition is not, demonstrating a separation between signaling and structural contributions of IAC components.

Bibliographic Details
Main Authors: Horton, Edward R., Humphries, Jonathan D., Stutchbury, Ben, Jacquemet, Guillaume, Ballestrem, Christoph, Barry, Simon T., Humphries, Martin J.
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739608/