CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts

CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts

Greenblatt et al. show that deletion of CHMP5 in osteoclasts leads to increased bone resorption coupled with exuberant osteoblast activity, resembling an early onset form of human Paget’s Disease of Bone

Bibliographic Details
Main Authors: Greenblatt, Matthew B., Park, Kwang Hwan, Oh, Hwanhee, Kim, Jung-Min, Shin, Dong Yeon, Lee, Jae Myun, Lee, Jin Woo, Singh, Anju, Lee, Ki-young, Hu, Dorothy, Xiao, Changchun, Charles, Julia F., Penninger, Josef M., Lotinun, Sutada, Baron, Roland, Ghosh, Sankar, Shim, Jae-Hyuck
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516796/

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