Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

The closely related tyrosine phosphatases PTPa and PTPe fulfill distinct roles in osteoclasts. The various effects of each PTP on podosome organization in osteoclasts are caused by their distinct N-termini. The function of PTPe in these cells requires the presence of its 12 N-terminal residues, in p...

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Bibliographic Details
Main Authors: Finkelshtein, Eynat, Lotinun, Sutada, Levy-Apter, Einat, Arman, Esther, den Hertog, Jeroen, Baron, Roland, Elson, Ari
Format: Online
Language:English
Published: The American Society for Cell Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038506/