Reprogramming of cell fate: epigenetic memory and the erasure of memories past

Cell identity is a reflection of a cell type-specific gene expression profile, and consequently, cell type-specific transcription factor networks are considered to be at the heart of a given cellular phenotype. Although generally stable, cell identity can be reprogrammed in vitro by forced changes t...

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Bibliographic Details
Main Authors: Nashun, Buhe, Hill, Peter WS, Hajkova, Petra
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491992/