Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP
Hepatocellular carcinomas (HCC) are highly malignant and aggressive tumors lack of effective therapeutic drugs. Piperlongumine (PL), a natural product isolated from longer pepper plants, is recently identified as a potent cytotoxic compound highly selective to cancer cells. Here, we reported that PL...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467445/ |