Chemical activation of the mechanotransduction channel Piezo1

Piezo ion channels are activated by various types of mechanical stimuli and function as biological pressure sensors in both vertebrates and invertebrates. To date, mechanical stimuli are the only means to activate Piezo ion channels and whether other modes of activation exist is not known. In this s...

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Bibliographic Details
Main Authors: Syeda, Ruhma, Xu, Jie, Dubin, Adrienne E, Coste, Bertrand, Mathur, Jayanti, Huynh, Truc, Matzen, Jason, Lao, Jianmin, Tully, David C, Engels, Ingo H, Petrassi, H Michael, Schumacher, Andrew M, Montal, Mauricio, Bandell, Michael, Patapoutian, Ardem
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456433/