Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicans
The major fungal pathogen of humans, Candida albicans, is exposed to reactive nitrogen and oxygen species following phagocytosis by host immune cells. In response to these toxins, this fungus activates potent anti-stress responses that include scavenging of reactive nitrosative and oxidative species...
Main Authors: | Tillmann, Anna T., Strijbis, Karin, Cameron, Gary, Radmaneshfar, Elahe, Thiel, Marco, Munro, Carol A., MacCallum, Donna M., Distel, Ben, Gow, Neil A. R., Brown, Alistair J. P. |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454436/ |
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