Expansion of Foxp3+ T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge

Expansion of Foxp3+ T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge

Candida albicans remains the fungus most frequently associated with nosocomial bloodstream infection. In disseminated candidiasis, the role of Foxp3+ regulatory T (Treg) cells remains largely unexplored. Our aims were to characterize Foxp3+ Treg-cell activation in a murine intravenous challenge mode...

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Bibliographic Details
Main Authors: Whibley, Natasha, MacCallum, Donna M, Vickers, Mark A, Zafreen, Sadia, Waldmann, Herman, Hori, Shohei, Gaffen, Sarah L, Gow, Neil A R, Barker, Robert N, Hall, Andrew M
Format: Online
Language:English
Published: Wiley-VCH Verlag GmbH & Co. KGaA 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992851/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992851/

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