Gadd45a promotes DNA demethylation through TDG

Growth arrest and DNA-damage-inducible protein 45 (Gadd45) family members have been implicated in DNA demethylation in vertebrates. However, it remained unclear how they contribute to the demethylation process. Here, we demonstrate that Gadd45a promotes active DNA demethylation through thymine DNA g...

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Bibliographic Details
Main Authors: Li, Zheng, Gu, Tian-Peng, Weber, Alain R., Shen, Jia-Zhen, Li, Bin-Zhong, Xie, Zhi-Guo, Yin, Ruichuan, Guo, Fan, Liu, Xiaomeng, Tang, Fuchou, Wang, Hailin, Schär, Primo, Xu, Guo-Liang
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417182/