Study of PTEN subcellular localization
The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, energy metabolism and death. The repertoire of roles f...
Main Authors: | Bononi, Angela, Pinton, Paolo |
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Format: | Online |
Language: | English |
Published: |
Academic Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396696/ |
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