Study of PTEN subcellular localization

The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, energy metabolism and death. The repertoire of roles f...

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Bibliographic Details
Main Authors: Bononi, Angela, Pinton, Paolo
Format: Online
Language:English
Published: Academic Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396696/