Study of PTEN subcellular localization
The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, energy metabolism and death. The repertoire of roles f...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Academic Press
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396696/ |