The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network
Nuclear exclusion of the PTEN tumour suppressor has been associated with cancer progression1-6. However, the mechanisms leading to this aberrant PTEN localization in human cancers are currently unknown. We have previously reported that ubiquitinylation of PTEN at specific lysine residues regulates i...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398484/ |